Andalas obstetrics and gynecology journal
Andalas Obstetrics And Gynecology Journal (AOJ) (e-ISSN: 2579-8324) is a peer-reviewed, open-access national journal published by Universitas Andalas and is dedicated to publish and disseminate research articles, literature reviews, and case reports, in the field of obstetrics, gynecology, and other related disciplines.
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<![CDATA[Differences of Magnesium Level Between Normal Pregnancy and Preeclamsia ]]>
<![CDATA[Rengga Pradipta]]>;
<![CDATA[Roza Sriyanti]]>;
<![CDATA[Hafni Bachtiar]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021) ]]>
Publisher : <![CDATA[Universitas Andalas ]]>
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DOI: 10.25077/aoj.5.1.63-68.2021
<![CDATA[Background: Preeclampsia is a multi-organ disorder that occurs in pregnant women with high blood pressure which is still difficult to predict. Until now, many theories have put forward the causes of preeclampsia, one of which is much debated is the lack of nutrition in pregnant women which can lead to preeclampsia. Several studies suggest that there is a relationship with the lack of micronutrient intake, especially magnesium, which causes preeclampsia, especially in developing countries. Magnesium deficiency is one possible factor causing severe preeclampsia. Magnesium plays a role in normal neuromuscular function, regulation of calcium, potassium and transport of sodium in the membrane as a regulation of the activation of ATP. Magnesium also plays a role in blood pressure regulation. Magnesium deficiency can lead to endothelial malfunction, hypertension and failure of the cardiovascular system. The role of magnesium is in enzyme reactions that bind to anaerobic glucose metabolism, the krebs cycle, fatty acid oxidation and reactions between coenzyme and fatty acids. Magnesium deficiency will result in changes to the nerves, muscles and blood vessels.Methods: Analytical observational study with cross sectional design in 17 women with preeclampsia and 17 normal pregnant women who met the inclusion and exclusion criteria. Research subjects were collected at Dr M Djamil Padang General Hospital, November 2019 to January 2020. Magnesium levels were checked by enzymatic methods. The difference in the mean magnesium preeclampsia and normal pregnancy was analyzed using independent t test.Results: Mean magnesium in preeclampsia was lower than normal pregnancy (1.61 ± 0.59aµg / ml vs 2.20 ± 0.18, p = 0.001).Conclusion: Mean magnesium level in preeclampsia was significantly lower than normal pregnancy..Keywords: Average levels of magnesium, magnesium, preeclampsia, normal pregnancy]]>
<![CDATA[Thanatophoric Dysplasia ]]>
<![CDATA[Vaulinne Basyir]]>;
<![CDATA[Yusrawati Yusrawati]]>;
<![CDATA[Gistin Husnul Khatimah]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021) ]]>
Publisher : <![CDATA[Universitas Andalas ]]>
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DOI: 10.25077/aoj.5.1.112-118.2021
<![CDATA[Background: The term tanatophorik comes from the Greek word thanatophorus which means "innate death" or "bearing death". The problem that underlies this disease is the process of bone formation. This disease is associated with an autosomal dominant inherited mutation of the fibroblast growth factor 3 receptor (FGFR3) gene on the arm of chromosome 4 (4p16.3). Because FGFR3 is the main modulator in bone formation, the typical clinical features of this disease include shortening of the extremities, curved femur, clover-like skull and narrowing of the thoracic cavity.Tanatophoric dysplasia is a skeletal disorder that is "lethal" or deadly. The deaths occurred due to respiratory failure caused by reduced chest cavity capacity, hypoplastic lungs and / or brainstem compression.Destination: Reported a case of thanatophoric dysplasiaMethod: Case Report Case Report: Case 33 years old woman, with preterm parturient G1P0A0H0 35-36 weeks 1 latent phase + history of 2x laparotomy + suspected fetal tanatophoric dysplasia. On ultrasound examination, it was found that BPD = 9.14 cm; AC = 30.56 cm; HC = 32.05 cm; FL = 2.55 cm; AFI; 9.06cm; SDAU = 1.72 cm. The presence of frontal bosing, saddle nose and micromilia (proximal, distal, phalanges) was found. The patient was planned for vaginal delivery and the progress of labor was followed. Patients provided informed consent regarding the possibility of fetal death during labor and after birth. During the active phase of the labor process, hypotony uterine innersia occurs and oxytocin drip is performed to accelerate labor. The baby was born male, weight 2175 grams, body length 34 cm and A / S: 1/0. Postmortem physical examination revealed macroscopic findings of tanatophoric dysplasia infants such as hypertelorism, low nasal bridge, cranio-facial disproportion. Narrow chest with protruding abdomen and short, bent limbs.Conclusion: Tanatophoric dysplasia is "lethal" skeletal dysplasia. Careful prenatal examination is required in diagnosis and termination of pregnancy. Keywords: Thanatophoric dysplasia, prenatal diagnosis]]>
<![CDATA[The Difference of Using Antibiotics Before and After Antimicrobial Resistance Control Program (PPRA) at RSUP Dr. M. Djamil Padang ]]>
<![CDATA[Ermawati Ermawati]]>;
<![CDATA[Daan Khambri]]>;
<![CDATA[Dedy Almasdy]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021) ]]>
Publisher : <![CDATA[Universitas Andalas ]]>
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DOI: 10.25077/aoj.5.1.29-42.2021
<![CDATA[Antibiotics have been proven to be beneficial for human life since their discovery. This type of drug is the most widely used in infections caused by bacteria. the function is to inhibit growth or kill microorganisms. Therefore, more than 30-80% of patients in developed countries who are hospitalized receive antibiotics, either alone or in combination. Evaluating the implementation of PPRA at RSUP. Dr. M. Djamil by comparing the evaluation of antibiotic use before and after the application of PPRA in inpatients in the Obgyn.We conducted this research including a type of correlational analytical research with a retrospective approach. The research sample was taken by the Medical Record room of the RSUP. Dr. M. Djamil Padang. The research was carried out for 1 month, from May 1 to May 31, 2020. The population in this research was all inpatients of Obstetrics and Gynecology in Dr. M. Djamil Padang.There was an increase in the percentage of antibiotic use in 2019 in line with the higher percentage of surgery in 2019 compared to 2018. As regulated by the guidelines for the use of antibiotics in Dr. M. Djamil, for surgery, prophylactic antibiotics are given 30 minutes before the procedure to prevent infection due to the invasive action. The use of prophylactic antibiotics whether to continue is determined by the type of operation, the length of the operation, the amount of bleeding during the operation, the clinical patient, the laboratory value.There were no significant changes in the implementation of PPRA's work on the qualitative analysis of antibiotic use.Keywords: Antibiotics, PPRA, Evaluation]]>
<![CDATA[The Effect of Oral Albumin Intake on Serum Albumin Levels in Preeclamsia Patients With Hypoalbuminemia in RSUP Dr. M. Djamil Padang ]]>
<![CDATA[Irwin Fitriansyah]]>;
<![CDATA[Dovy Djanas]]>;
<![CDATA[Hafni Bachtiar]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021) ]]>
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DOI: 10.25077/aoj.5.1.69-81.2021
<![CDATA[Introduction : Albumin main function is maintaining the plasma colloid oncotic pressure. Preeclampsia cause a decrease in serum albumin in the pregnant woman. Low albumin levels increase mortality, longer wound healing and longer hospital stays. The intake of oral albumin is expected to be effective in increasing the level of albumin in the blood.Objective : To determine the effect of freeze dryer method intake compared to liquid snakehead fish extract in patients with preeclampsia and hypoalbuminemia.Material and methods : Using pre and post-test control group design.The total sample was 38 patients with severe preeclampsia with hypoalbuminemia, divided into control and intervention groups. Control was given the intake of liquid snakehead fish extract, in the intervention was given the Freeze dryer method. The research data were analyzed using the Mann Whitney test method and the Wilcoxon test.Results : In the intervention group the mean pretest albumin level was 2.66 ± 0.17 gr / dl and on the 4th day it was 3.13 ± 0.16 gr / dl (p = 0.000). In the control group the mean pretest albumin level was 2.72 ± 0.15 gr / dl and on the 4th day it became 3.06 ± 0.14 gr / dl (p = 0.000). On the 4th day after treatment, the increase in serum albumin levels in the intervention group was 0.47 ± 0.19 gr / dl; whereas in the control group was 0.34 ± 0.10 gr / dl with a value of p = 0.031 (p <0.05).Conclusion : The freeze dryer method (freeze dryer method ) for the Cork Fish Extract resulted in a higher increase in albumin levels than the liquid snakehead fish extract.Keywords: Preeclampsia, Hypoalbuminemia, freeze dryer method of Snakehead Fish Extract]]>
<![CDATA[A Case of Prenatal Diagnosis of Turner Syndrome with Ultrasonography ]]>
<![CDATA[Yusrawati Yusrawati]]>;
<![CDATA[Dona Mirsa Putri]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021) ]]>
Publisher : <![CDATA[Universitas Andalas ]]>
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DOI: 10.25077/aoj.5.1.119-129.2021
<![CDATA[Objective: To report a case of Turner syndrome diagnosed in prenatal care.Method: A case report.Case: Case of Mrs. Y 26-year-old woman G2P1A0L1 diagnosed on 19-20 weeks of gestation with Turner syndrome. Ultrasound examination findings were hydrops fetalis on the neck region, multiple septated cystic masses, subcutaneous edema, ascites, and hydrothorax. Subsequently, amniocentesis was performed and the chromosome analysis result showed Turner syndrome (45, X0). The patient was induced vaginal delivery on 22-23 weeks of pregnancy due to intrauterine fetal death indication. The baby was born with ambiguous genitalia, birth weight 500 grams, birth length 22 centimeters, and Apgar’s score was 0/0. The congenital anomalies discovered include subcutaneous edema, ascites, hydromacolly, and hydrops fetalis.Conclusion: Turner syndrome can be diagnosed at a prenatal period by ultrasound examination. Keywords: Turner Syndrome, Hydrops Fetalis, Ultrasonography]]>
<![CDATA[Reproductive Health Knowledge of Adolescent in Padang: Case Study of SMA N 1 Students ]]>
<![CDATA[Aladin Aladin]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021) ]]>
Publisher : <![CDATA[Universitas Andalas ]]>
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DOI: 10.25077/aoj.5.1.43-49.2021
<![CDATA[The aim of this study is to describe the knowledge level and accuracy of reproductive health among students at SMA N 1 Padang. The study design was analytical survey with cross-sectional approach. The population were all SMA N 1 students while cluster random sampling was applied to get 267 students as respondents which represented each major (natural science or social science) and class (X, XI, and XII). The questionnaires were divided into several sections consisting the general knowledge of reproductive health, contraception, and sexually transmitted disease (STD). Result of the study showed that students in natural science major (scoring 71.9%) were having better knowledge than students in social science major (scoring 51.8%). It was also found that students in grade XII (scoring 67.7%) were getting highest result compared to students in grade XI (scoring 61.4%) and grade X (scoring 67.1%). Nevertheless, the result was not satisfying, considering that the average score of all students were only 65.6%. Therefore, guidance from parents, teachers, as well as counselling unit are crucial to help adolescent in Padang, in the context of reproductive health knowledge.]]>
<![CDATA[The Difference in Average of Maternal Serum Hypoxia-Inducible Factors-1α Levels between Early Onset and Late-Onset Severe Preeclampsia ]]>
<![CDATA[David Perdana]]>;
<![CDATA[Defrin Defrin]]>;
<![CDATA[Firdawati Firdawati]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021) ]]>
Publisher : <![CDATA[Universitas Andalas ]]>
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DOI: 10.25077/aoj.5.1.82-89.2021
<![CDATA[The purpose of this study is to know the difference average of maternal serum levels of HIF-1α between early-onset and late-onset severe preeclampsia. This study used a cross sectional comparative study design that conducted in Februari 2020 - Agustus 2020 in the SMF / Obstetrics and Gynecology department of RSUP dr. M. Djamil Padang, RSUD Achmad Mochtar, RSUD Pariaman, RSUD M Zein Painan. We used consecutive sampling method which consists of 60 pregnant women who fulfill the inclusion and exclusion criteria. They were divided into two groups early-onset severe preeclampsia and late-onset severe preeclampsia. HIF-1α tests were done using ELISA method. The average of maternal serum levels of HIF-1α in late-onset severe preeclampsia is found to be the highest when compared to the early-onset severe preeclampsia, 1,37 ± 1,08 ng/ml vs 0,69 ± 0,11 ng/ml. This difference is significant with the Mann-whitney non parametrical statistical test (p <0.05). There is a significant difference average of maternal serum levels of HIF-1α between early-onset and late-onset severe preeclampsiaKeywords: early onset severe preeclampsia, late onset preeclampsia late onset, maternal serum levels of HIF-1α]]>
<![CDATA[Premature Ovarian Failure and Epilepsy ]]>
<![CDATA[Hendra Permana]]>;
<![CDATA[Afriyeni Sri Rahmi]]>;
<![CDATA[Syamel Muhammad]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021) ]]>
Publisher : <![CDATA[Universitas Andalas ]]>
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DOI: 10.25077/aoj.5.1.1-8.2021
<![CDATA[Premature ovarian failure (POF) or premature menopause refers to development of amenorrhoea due to cessation of ovarian function before the age of 40 years. The diagnosis is based on elevated FSH levels in menopausal range (usually above 40 IU/l) detected on at least two occasions a few weeks apart. The term “epilepsy” defines a group of disorders characterized by an enduring predisposition of the brain to produce seizures. The hypothalamic-pituitary-ovarian axis regulation is affected by the abnormal neurophysiology of seizures, and the hypothalamic-pituitary-ovarian associated hormones are affected by medications used to treat seizures in women with epilepsy. Ictal and interictal discharges can disrupt the normal activity of brain structures, including the limbic system, amygdala, hypothalamus, and pituitary gland. Management of epilepsy in women requires not only knowledge of epilepsy, but also recognition of the various roles and priorities women have in their lives (education, career development, child rearing, the role as carer within the extended family), and attention to gender-specific issues and their impact on patients’ wellbeing throughout life.Keywords: premature ovarian failure (POF), epilepsy]]>
<![CDATA[Primary Fallopian Tube Carcinoma : A Case Report ]]>
<![CDATA[Rijalul Abrar]]>;
<![CDATA[Syamel Muhammad]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021) ]]>
Publisher : <![CDATA[Universitas Andalas ]]>
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DOI: 10.25077/aoj.5.1.130-138.2021
<![CDATA[Objective: To report the case of primary fallopian tube carcinoma metastatic to cervix and omentum, but not infiltrate the ovariumMethod: Case Report Case: A 40 years old woman presented with gradual onset pain and swelling of the abdomen. The patient was diagnosed with suspected ovarian carcinoma. After examination, the patient prepared for laparotomy; salpingo-oophorectomy, omentectomy, mass resection from pelvic and rectum Result: The hystological examination result was high grade serous carcinoma from the fallopian tube metastasis to cavum douglas and omentum. This case is a rare case because the tubal carcinoma was metastasis to cavum douglas and omentum without infiltrate the ovarium.Discussion: Primary carcinoma of the fallopian tube is rare and accounts for about 0.14-1.8% of all gynecological malignancies. Clinically the diagnose of tubal carcinoma very similar to ovarian cancer, the diagnose can not distinguished pre operative. The new staging of FIGO may be reference for diagnostic and treatment of the desease. Thorough staging laparotomy is an important part of early management and systemic treatment. Keywords: tubal carcinoma, PFTC, metastasis, high grade serous carcinoma]]>
<![CDATA[Relationship between Husband's Support, Knowledge Level, and Motivation with IVA Examination Behavior in Women of Childbearing ge in Padang City ]]>
<![CDATA[Intan Firmana Putri]]>;
<![CDATA[Ferdinal Ferry]]>;
<![CDATA[Hafni Bachtiar]]>
<![CDATA[ Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021) ]]>
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DOI: 10.25077/aoj.5.1.50-55.2021
<![CDATA[Background: Cancer is the second leading cause of death in the world. Cervical cancer is in the 9th position out of 35 types of cancer causing the most deaths in the world. Cervical cancer is the second highest type of cancer after breast cancer in women, which affects more than 1.4 million women worldwide. Every year more than 460,000 cervical cancer incidents occur and about 231,000 women die from the disease.Objectives: This study aims to determine the relationship between husband's support, level of knowledge and motivation, with the behavior of IVA examination in fertile aged women in the city of Padang.Methods: This research is an analytic observational study with cross-sectional comparative study approach that looks at the relationship between knowledge, motivation, and husband's support with IVA examination behavior in women of childbearing age.Results: The percentage who did not perform IVA examination was higher among respondents with low motivation compared to those with high motivation, namely 54.7% versus 45%. Statistically this difference was not significant (p> 0.05). The number of respondents who did not perform IVA examinations was higher for respondents with less husband's support, namely 32 respondents (42.1%) and more than half of respondents who did IVA examinations, namely 44 respondents (57.9%) who received less support from their husbands. Statistically this difference was significant (p <0.05).Conclusion: There is a relationship between the level of knowledge and the behavior of the IVA examination, there is no relationship between motivation and the behavior of the IVA examination and there is a relationship between the level of knowledge and the behavior of the IVA examination.Keywords: IVA, women of childbearing age, education]]>
